Find stopping boundary via binomial exact tests

Find stopping boundary via binomial exact tests

findbound(n, alpha_test = 0.025, pH0 = 0.5, alternative = "greater")

Arguments

n

total number of events

alpha_test

nominal alpha for the binomial test

pH0

proportion of events in the experimental arm under the null hypothesis, typically based on randomization ratio (e.g. 0.5 for a 1:1 randomization)

alternative

direction of alternative, "less" or "greater"

Value

number of events in the experimental group that would lead to a stopping

Examples

findbound(n=20, alpha_test=0.025, pH0 = 0.5, alternative="greater")
#> [1] 15
findbound(n=20, alpha_test=0.025, pH0 = 0.5, alternative="less")
#> [1] 5